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With a specific focus on dietary restriction, insulin administration and the insulin-lowering drug diazoxide, such modifications of the insulin/IGF-1 system are the topic of this review

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Patients who maintained strict calorie restriction without medication still experienced weight gain, though typically at a slower rate than those who did not adjust their eating habits

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Cell lysis buffer for western blot and IP was purchased from Beyotime Institute of Biotechnology (Haimen, Jiangsu, China, P0013)